HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-(1-hydroxy-2-phenoxyethyl)pyrrolidine → (2S)-1-(N-benzyloxycarbonyl-L-prolyl)-2-(phenoxyacetyl)-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-(1-hydroxy-2-phenoxyethyl)pyrrolidine | HCID 57049295 | — |
| Reactant | Dmso dcc | HCID 86749402 | — |
| Product | (2S)-1-(N-benzyloxycarbonyl-L-prolyl)-2-(phenoxyacetyl)-pyrrolidine | HCID 15297819 | 83.8% |
Reaction Steps
(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-(1-hydroxy-2-phenoxyethyl)pyrrolidine (393 mg) was subjected to DMSO-DCC oxidation in the same manner as in Example 1-D) to give 328 mg of (2S)-1-(N-benzyloxycarbonyl-L-prolyl)-2-(phenoxyacetyl)-pyrrolidine (See Table 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-5192bc4a33cf4df0856edccb8576672e |
| Source note | uspto-grants-1996_04 |