HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → (2S)-2-[1-Hydroxy-2-(phenylsulfinyl)ethyl]-1-[N-(4-phenylbutyryl)-L-prolyl]pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | (2S)-2-[1-Hydroxy-2-(phenylthio)ethyl]-1-[N-(4-phenyl-butyryl)-L-prolyl]pyrrolidine | HCID 70048625 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (2S)-2-[1-Hydroxy-2-(phenylsulfinyl)ethyl]-1-[N-(4-phenylbutyryl)-L-prolyl]pyrrolidine | HCID 70049848 | — |
Reaction Steps
(2S)-2-[1-Hydroxy-2-(phenylthio)ethyl]-1-[N-(4-phenyl-butyryl)-L-prolyl]pyrrolidine (1.25 g) was subjected to oxidation in the same manner as in Example 2-A) in dichloromethane (9 ml) using 1.1 equivalent of m-chloroperbenzoic acid to give 1.18 g of (2S)-2-[1-hydroxy-2-(phenylsulfinyl)ethyl]-1-[N-(4-phenylbutyryl)-L-prolyl]-pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-81df56d206034e69957b1466af20c8ac |
| Source note | uspto-grants-1996_04 |