HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[1-hydroxy-2-(4-nitrophenylsulfinyl)ethyl]pyrrolidine → (2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[(4-nitrophenylsulfinyl)acetyl]pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[1-hydroxy-2-(4-nitrophenylsulfinyl)ethyl]pyrrolidine | HCID 56997501 | — |
| Reactant | Dmso dcc | HCID 86749402 | — |
| Product | (2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[(4-nitrophenylsulfinyl)acetyl]pyrrolidine | HCID 57138399 | 76.5% |
Reaction Steps
(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[1-hydroxy-2-(4-nitrophenylsulfinyl)ethyl]pyrrolidine (883 mg) was subjected to DMSO-DCC oxidation as in Example 1-D) to give 673 mg of the title compound (See Table 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-1bbc771c5caa4b0687d801183794398f |
| Source note | uspto-grants-1996_04 |