反应详情

(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-{1-hydroxy-2-[(S)-phenylsulfinyl]ethyl}pyrrolidine (600 mg) was subjected to DMSO-DCC oxidation as in Example 1-D), followed by purification of the reaction product by medium pressure silica gel column chromatography (eluate; chloroform:methanol=99.5: 0.5) to give 242 mg of the title compound (See Table 3 ).

1. customfollowed by purification of the reaction product by medium pressure silica gel column chromatography (eluate; chloroform:methanol=99.5: 0.5)