HuagongsheHuagongshe Chemistry Print Report · For research reference only
Monobenzone → (2S)-2-{2-[4-(Benzyloxy)phenoxy]-1-hydroxyethyl}-1-(tert-butoxycarbonyl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Monobenzone | HCID 7638 | — |
| Reactant | tert-butyl (2S)-2-(oxiran-2-yl)pyrrolidine-1-carboxylate | HCID 15297813 | — |
| Product | (2S)-2-{2-[4-(Benzyloxy)phenoxy]-1-hydroxyethyl}-1-(tert-butoxycarbonyl)pyrrolidine | HCID 57047086 | 59.1% |
Reaction Steps
By the same procedure as in Example 26-B), while using (2S)-1-(tert-butoxycarbonyl)-2-(1,2-epoxyethyl)pyrrolidine (1.50 g) and 4-(benzyloxy)phenol (2.96 g), there was obtained 1.72 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-5eae28f4bd584fe69cb6419cf358b704 |
| Source note | uspto-grants-1996_04 |