HuagongsheHuagongshe Chemistry Print Report · For research reference only
Capryloyl proline → (2S)-2-(1-Hydroxy-2-phenoxyethyl)-1-(N-octanoyl-L-prolyl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Capryloyl proline | HCID 18632639 | — |
| Reactant | (2S)-1-(t-butoxycarbonyl)-2-(1-hydroxy-2-phenoxyethyl)-pyrrolidine | HCID 57278887 | — |
| Product | (2S)-2-(1-Hydroxy-2-phenoxyethyl)-1-(N-octanoyl-L-prolyl)pyrrolidine | HCID 57232189 | 55.2% |
Reaction Steps
By the same procedure as in Example 1-D), while using (2S)-1-(tert-butoxycarbonyl)-2-(1-hydroxy-2-phenoxyethyl)pyrrolidine (1.50 g) and N-octanoyl-L-proline (1.18 g), there was obtained 1.16 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-dba6e328d4794d15a231434a31e2b557 |
| Source note | uspto-grants-1996_04 |