HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 67771546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | HCID 67771609 | HCID 67771609 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 67771546 | HCID 67771546 | 59.3% |
Reaction Steps
(2S)-2-[1-Hydroxy-2-(4-methoxyphenoxy)ethyl]-1-[N-(N-phenylglycyl)-L-prolyl]pyrrolidine (488 mg) was treated in the same manner as in Example 47-D) using DMSO (3 ml), benzene (1.5 ml), triethylamine (0.73 ml+0.15 ml), and sulfur trioxide-pyridine complex (778 mg) to give 288 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-6dbdc1ab52e74809bb0e2106d002ec62 |
| Source note | uspto-grants-1996_04 |