HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 70269062, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | HCID 67771267 | HCID 67771267 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 70269062 | HCID 70269062 | 82.6% |
Reaction Steps
(2S)-2-[1-Hydroxy-2-(4-methoxyphenoxy)ethyl]-1-{N-[(phenylthio)acetyl]-L-prolyl}pyrrolidine (620 mg) was treated in the same manner as in Example 47-D) using DMSO (10 ml), benzene (5 ml), triethylamine (0.90 ml), and sulfur trioxide-pyridine complex (960 mg) to give 510 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-965c749b6e5a4592bbe458e4c44cc8fb |
| Source note | uspto-grants-1996_04 |