HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tirilazad Mesylate → HCID 14307852, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tirilazad Mesylate | HCID 104902 | — |
| Reactant | Tirilazad | HCID 104903 | — |
| Reactant | HCID 18649329 | HCID 18649329 | — |
| Reactant | HCID 67766221 | HCID 67766221 | — |
| Product | HCID 14307852 | HCID 14307852 | — |
Reaction Steps
The preferred amino substituted steroid (XI) is 16α-methyl-21-[4[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]pregna-1,4,9(11)-triene-3,20-dione. More preferred is 16α-methyl-21-[4-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]pregna1,4,9(11)-triene-3,20-dione monomethanesulfonate, 16α-methyl-21-[4-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]pregna1,4,9(11)-triene-3,20-dione bismethanesulfonate and 16α-methyl-21-[4-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]pregna-1,4,9(11)-triene-3,20-dione hydrochloride. Most preferred is 16α-methyl-21-[4-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl]pregna-1,4,9(11)-triene-3,20-dione monomethanesulfonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506354 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-1c77aa23dfdf4498a80a50d7b5820e8e |
| Source note | uspto-grants-1996_04 |