HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (4-(6,7-Bis(stearyloxy)-4-thiaheptanoylamino)benzoyl)glutamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (4-(6,7-Bis(stearyloxy)-4-thiaheptanoylamino)benzoyl)glutamic acid di-t-butyl ester | HCID 53695392 | — |
| Product | (4-(6,7-Bis(stearyloxy)-4-thiaheptanoylamino)benzoyl)glutamic acid | HCID 53849118 | 94% |
Reaction Steps
To (4-(6,7-bis(stearyloxy)-4-thiaheptanoylamino)benzoyl)glutamic acid di-t-butyl ester as obtained in Example 25 (75 mg), trifiuoroacetic acid (5 ml) was added, followed by stirring at room temperature for 24 hours. The mixture was concentrated to yield the title compound (64 mg, yield 94%) as a colorless crystal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506267 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-cb20f8d6a0614b1ab398eb740a8b5431 |
| Source note | uspto-grants-1996_04 |