Trifluoroacetic acid → HCID 10843463, compound

Participants

Reaction Steps

A solution of 4-[6,7-bis(palmitoyloxy)-4-thiaheptanoylaminomethyl]benzoyl-glutamic acid di-t-butyl ester as obtained in Example 39 (325 mg) in dichloromethane (0.5 ml)-trifiuoroacetic acid (1 ml) was stirred at room temperature for 30 minutes. After solvent concentration under reduced pressure, the resulting residue was crystallized from methanol-water to yield the title compound (231 mg, yield 80%) as a colorless powder.

Provenance & Evidence