HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[6,7-Bis(12-phenyldodecanoyloxy)-4-thiaheptanoylamino]benzoylglutamic acid di-t-butylester → 4-[6,7-Bis(12-phenyldodecanoyloxy)-4-thiaheptanoylamino]benzoylglutamic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[6,7-Bis(12-phenyldodecanoyloxy)-4-thiaheptanoylamino]benzoylglutamic acid di-t-butylester | HCID 11804212 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 4-[6,7-Bis(12-phenyldodecanoyloxy)-4-thiaheptanoylamino]benzoylglutamic acid | HCID 10605882 | 84% |
Reaction Steps
A solution of 4-[6,7-bis(12-phenyldodecanoyloxy)-4-thiaheptanoylamino]benzoyl-glutamic acid di-t-butyl ester as obtained in Example 60 (275 mg) in trifiuoroacetic acid (2 ml) was stirred at room temperature for 2 hours, after which the solvent was distilled off under reduced pressure, to yield the title compound (207 mg, yield 84%) as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506267 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-c4baee13994a485fb56b08faad38ede7 |
| Source note | uspto-grants-1996_04 |