Trifluoroacetic acid → HCID 10724519, compound

Participants

Reaction Steps

A solution of 4-[6,7-bis(palmitoyloxy)-4-thiaoctanoylaminomethyl]benzoyl-glutamic acid di-t-butyl ester as obtained in Example 75 (574 mg) in methylene chloride (4 ml)-trifiuoroacetic acid (5 ml) was stirred at room temperature for 4 hours, after which the solvent was distilled off under reduced pressure. The residue was recrystallized from methanolwater to yield the title compound (505 mg, yield 99%) as a colorless powder.

Provenance & Evidence