Phenol → Diglycidyl ether

Participants

Reaction Conditions

Reaction Steps

5.28 g of a phenol derivative represented by the following formula: ##STR19## 11.55 g of S-(+)-epichlorohydrin (chemical purity: 98.5% or more, optical purity: 99% or more), 3.00 g of potassium tert-butoxide and 45 ml of tert-butyl alcohol were mixed and stirred for 3 hours at 60° C. After evaporating the solvent from the reaction mixture at reduced pressure, the resultant was subjected to extraction with chloroform followed by evaporation of the solvent. The residue was purified by a silica gel column chromatography to obtain 5.82 g of a R-isomer of glycidyl ether represented by the following formula (Intermediate 2). ##STR20##

Provenance & Evidence