Triethylamine → HCID 44211256, compound

Participants

Reaction Steps

The title compound was prepared by the method of Example 3, using pyridazine-4-carboxylic acid (0.5 g, 4 mmol), aminoindole (D2, 0.59 g, 4 mmol), triethylamine (0.57 ml) and diphenylphosphoryl azide (0.86 ml, 4.1 mmol) in 1,4-dioxan (40 ml). Crude product was chromatographed on silica (75 g) eluted with 5-10% methanol/dichloromethane. The second component was extracted with hot methanol to give an insoluble residue of pure title compound (0.11 g). mp 216°-221° C.

Provenance & Evidence