HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic Acid → 1-Pentanamine, N-methyl-N-2-propynyl-, ethanedioate (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic Acid | HCID 971 | — |
| Reactant | 1-Bromopentane | HCID 8057 | — |
| Reactant | N-methylpropyn-2-ylamine | HCID 96160 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Pentanamine, N-methyl-N-2-propynyl-, ethanedioate (1:1) | HCID 3072567 | 60% |
Reaction Steps
1-Bromopentane (12.1 g, 80 mmoles) and N-methylpropargylamine (11.1 g, 160mmoles) were refluxed in absolute ethanol (75 mL) for 72 h. to give (after addition to 80 mmoles of oxalic acid in ether) the title compound in 60% yield after recrystallization from methanol-ether, m.p.=101°-103° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05508311 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-621cb448a756477788fcfe53f27419a4 |
| Source note | uspto-grants-1996_04 |