HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl alpha-(hydroxy methylene)-2-isopropyl-4-[(E)-styryl]-5-thiazolacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 67766585 | HCID 67766585 | — |
| Product | Methyl alpha-(hydroxy methylene)-2-isopropyl-4-[(E)-styryl]-5-thiazolacetate | HCID 67766718 | — |
Reaction Steps
2 g of the enamine of Step F, 20 ml of tetrahydrofuran and 5 ml of a 2N hydrochloric acid solution were mixed together under nitrogen and left for 5 hours at 20° to 21° C. The tetrahydrofuran was evaporated off and the product was used as is for the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05508414 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-34c0981ed9824859acc40564af7ecf9a |
| Source note | uspto-grants-1996_04 |