L-Aspartic Acid → L-Aspartic Acid
Reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5].[S:10]([O-:14])([O-:13])(=[O:12])=[O:11].[Na+].[Na+]>>[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=[O:5].[S:10]([O-:14])([O-:13])(=[O:12])=[O:11].[NH4+:1].[NH4+:1]Participants
Procedure
The reaction mixture of aspartic acid and sodium sulfate at a reaction temperature of about 170° C. in Example 48 produced polysuccinimide of higher Mw than that which was obtained with a reaction mixture of aspartic acid and ammonium sulfate in Example 39 but of only slightly higher Mn. At higher reaction temperatures, however, there was substantially no observable differences between the use of either sodium sulfate or ammonium sulfate, based on the Mw of the 10 polysuccinimide produced. On the other hand, there was substantial improvement in the Mw of polysuccinimide produced from a reaction mixture of aspartic acid, sodium sulfate and sulfuric acid. As seen in Example 51 polysuccinimide of a Mw as high as about 11,971 was produced at a reaction temperature of about 240° C.
Sources & evidence
- ORD record
- ord-f36ff302555541bca5a0a848f2a7947d
- Source dataset
- uspto-grants-1996_04
- Patent number
- US05508434
Reaction notes
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