HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetraglyme → 2-(4-Methoxy-3-nitrophenylamino)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetraglyme | HCID 8925 | — |
| Reactant | 2-Chloroethyl chloroformate | HCID 12305 | — |
| Reactant | Benzenamine, 4-methoxy-3-nitro- | HCID 123071 | — |
| Reactant | Calcium Hydroxide | HCID 6093208 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 2-(4-Methoxy-3-nitrophenylamino)ethanol | HCID 14453741 | — |
Reaction Steps
A mixture of 168.2 g of 4-amino-2-nitroanisole, 42.8 g of calcium hydroxide and 5 g of tetraethylene glycol dimethylether in 1500 g of aqueous monoethylene glycol dimethylether is reacted in accordance with the instructions of Example 1 with 150 g of 2-chloroethyl chloroformate and, after separation of the phases, with 370.6 g of 50% strength potassium hydroxide. After working up analogously to Example 1, yellow-red crystals are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05508467 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-20b4fec4bd15430c94461196959bfef9 |
| Source note | uspto-grants-1996_04 |