2,2-Diethylbutanedioic acid → 4-[3-(6,7-Difluoro-2-quinolinylmethoxy)phenylamino]-2,2-diethyl-4-oxobutanoic acid

Participants

Reaction Steps

Analogously to Example 3, the title compound is prepared from 2,2-diethylsuccinic acid and 3-(6,7-difluoro-2-quinolinylmethoxy)aniline. It is obtained in the form of a white solid; 1H-NMR, 200 MHz, DMSO, delta (ppm)=9.90 (s, 1H), 8.42 (d, 1H), 8.10 (m, 2H), 7.70 (d, 1H), 7.45 (m, 1H), 7.07 (m, 2H), 6.73 (d, 1H), 5.35 (s, 2H), 2.58 (s, 2H), 1.80 (m, 4H), 0.80 (t, 6H).

Provenance & Evidence