Dihydro-3,3-diethyl-2,5-furandione → 4-[3-(7-Methyl-2-quinolinylmethoxy)phenylamino]-2,2-diethyl-4-oxobutanoic acid

HRID 1721185Notes

Reaction equation

HRID 1721185 reaction equation
[CH2:1]([C:3]1([CH2:10][CH3:11])[CH2:8][C:7](=[O:9])[O:6][C:4]1=[O:5])[CH3:2].[CH3:12][C:13]1[CH:22]=[C:21]2[C:16]([CH:17]=[CH:18][C:19]([CH2:23][O:24][C:25]3[CH:26]=[C:27]([CH:29]=[CH:30][CH:31]=3)[NH2:28])=[N:20]2)=[CH:15][CH:14]=1>>[CH3:12][C:13]1[CH:22]=[C:21]2[C:16]([CH:17]=[CH:18][C:19]([CH2:23][O:24][C:25]3[CH:26]=[C:27]([NH:28][C:7](=[O:9])[CH2:8][C:3]([CH2:10][CH3:11])([CH2:1][CH3:2])[C:4]([OH:6])=[O:5])[CH:29]=[CH:30][CH:31]=3)=[N:20]2)=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 137741Dihydro-3,3-diethyl-2,5-furandioneHCID 224169353-(7-Methyl-2-quinolinylmethoxy)aniline

Product 1

HCID 224169294-[3-(7-Methyl-2-quinolinylmethoxy)phenylamino]-2,2-diethyl-4-oxobutanoic acid

Procedure

The title compound is prepared analogously to the compound described in Example 20 from 2,2-diethylsuccinic acid anhydride and 3-(7-methyl-2-quinolinylmethoxy)aniline; colourless crystals of m.p. 162°-163°.

Sources & evidence

ORD record
ord-878ea9b86a6a4fa2abb610b2a17e13c7
Source dataset
uspto-grants-1996_04
Patent number
US05508408

Reaction notes

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