Dihydro-3,3-diethyl-2,5-furandione → 4-[3-(7-Methoxy-2-quinolinylmethoxy)phenylamino]-2,2-diethyl-4-oxobutanoic acid

HRID 1721186Notes

Reaction equation

HRID 1721186 reaction equation
[CH2:1]([C:3]1([CH2:10][CH3:11])[CH2:8][C:7](=[O:9])[O:6][C:4]1=[O:5])[CH3:2].[CH3:12][O:13][C:14]1[CH:23]=[C:22]2[C:17]([CH:18]=[CH:19][C:20]([CH2:24][O:25][C:26]3[CH:27]=[C:28]([CH:30]=[CH:31][CH:32]=3)[NH2:29])=[N:21]2)=[CH:16][CH:15]=1>>[CH3:12][O:13][C:14]1[CH:23]=[C:22]2[C:17]([CH:18]=[CH:19][C:20]([CH2:24][O:25][C:26]3[CH:27]=[C:28]([NH:29][C:7](=[O:9])[CH2:8][C:3]([CH2:10][CH3:11])([CH2:1][CH3:2])[C:4]([OH:6])=[O:5])[CH:30]=[CH:31][CH:32]=3)=[N:21]2)=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 137741Dihydro-3,3-diethyl-2,5-furandioneHCID 224168503-(7-Methoxy-2-quinolinylmethoxy)aniline

Product 1

HCID 224168784-[3-(7-Methoxy-2-quinolinylmethoxy)phenylamino]-2,2-diethyl-4-oxobutanoic acid

Procedure

The title compound is prepared analogously to the compound described in Example 20 from 2,2-diethylsuccinic acid anhydride and 3-(7-methoxy-2-quinolinylmethoxy)aniline; colourless crystals of m.p. 163°-164°.

Sources & evidence

ORD record
ord-7c527b2fd5dd421d951952b917896c65
Source dataset
uspto-grants-1996_04
Patent number
US05508408

Reaction notes

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