HCID 22914116, compound → HCID 22914108, compound

Participants

Reaction Steps

The tetrahydrofuran mixture from Example 13, 35.5 g at 96.7% (0.154 mole) was hydrogenated at 60 psi at 40°-50° C. using 0.75 g of 5% Pd on carbon. The crude product, 35.7 g, was distilled to yield 34.4 g of purified product (100% yield). BP 53° C./0.04 mmHg; 1H-NMR (300 MHz), spectra consistent with assigned structures. 13C-NMR (75 MHz), spectra consistent with assigned structures. IR (Neat), 2990, 1490, 1130, 1110 cm-1 ; MS (m/e), 209 (M+ -15), 110, 96 (Base);

Provenance & Evidence