Cyclopentylamine → HCID 19428501, compound

HRID 1721300Notes

Reaction equation

HRID 1721300 reaction equation
Cl[C:2]1[N:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[N:3]=1.[CH:10]1([NH2:15])[CH2:14][CH2:13][CH2:12][CH2:11]1>>[CH:10]1([NH:15][C:2]2[N:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[N:3]=2)[CH2:14][CH2:13][CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 2906CyclopentylamineHCID 773782,4,6-Trichloropyrimidine

Product 1

HCID 19428501HCID 19428501, compoundYield 35.2%

Procedure

The reaction of 2,4,6-trichloropyrimidine with cyclopentylamine carried out as described in Example 35 gives both compounds. The less polar 2-cyclopentylamino-4,6-dichloropyrimidine is obtained in a yield of 35.2%, m.p.: 48°-52° C.

Workup

  1. customgives both compounds

Sources & evidence

ORD record
ord-3b960a3874b245758a7caa4173f9087a
Source dataset
uspto-grants-1996_04
Patent number
US05510345

Reaction notes

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