Dimethylformamide → HCID 54157125, compound

Participants

Reaction Steps

To 32.5 g of a toluene solution containing 9.40 g (30.0 mmol, E/Z=22/78) of α-methoxyimino-2-(2,5-dimethylphenoxymethyl)phenylacetic acid produced in accordance with Example 5-(1) and 0.132 g (1.8 mmol) of dimethylformamide was added dropwise 4.64 g (39.0 mmol) of thionyl chloride over 5 hours while keeping at 60°-65° C., and the reaction was subsequently allowed to proceed at the same temperature for 2 hours, which afforded 34.1 g of a toluene solution of α-methoxyimino-2-(2,5-dimethylphenoxymethyl)phenylacetyl chloride.

Provenance & Evidence