1-Hydroxybenzotriazole → ethyl 2-[4-[[5-ethyl-4-(trifluoromethyl)-1H-imidazole-2-carbonyl]amino]-3-methoxypiperidin-1-yl]-5-methyl-1,3-thiazole-4-carboxylate
Reaction equation
[CH2:21]([CH3:22])[c:23]1[c:24]([C:31]([F:32])([F:33])[F:34])[n:25][c:26]([C:28](=[O:29])[OH:30])[nH:27]1.[NH2:1][CH:2]1[CH:3]([O:19][CH3:20])[CH2:4][N:5]([c:8]2[s:9][c:10]([CH3:18])[c:11]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[n:12]2)[CH2:6][CH2:7]1.[OH:35][n:36]1[c:37]2[c:38]([cH:39][cH:40][cH:41][cH:42]2)[n:43][n:44]1>>[NH:1]([CH:2]1[CH:3]([O:19][CH3:20])[CH2:4][N:5]([c:8]2[s:9][c:10]([CH3:18])[c:11]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[n:12]2)[CH2:6][CH2:7]1)[C:28]([c:26]1[n:25][c:24]([C:31]([F:32])([F:33])[F:34])[c:23]([CH2:21][CH3:22])[nH:27]1)=[O:29]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-44c49f64e1c44cab84d11bd27000a3c1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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