Water → HCID 67781296, compound

Participants

Reaction Steps

0.826 g (7.23 mmol) of (1R,2R)-(-)-1,2-cyclohexanediamine of α!D20 =-36.7° (c 4.14, H2O) and 1.04 g (7.21 mmol) of dl-trans-1,2-cyclooctanediol were added to 2 ml of toluene and then heated/dissolved therein, and the solution was cooled to room temperature. Afterward, the precipitated crystals were collected by filtration and then recrystallized from 2 ml of toluene twice to obtain 0.735 g of (1R,2R)-(-)-1,2-cyclohexanediamine·(1R,2R)-(-)-1,2-cyclooctanediol. Physical properties of the product are as follows.

Provenance & Evidence