Boron tribromide → N-formyl-3,4-dihydroxy-6-iodo-L-phenylalanine ethyl ester

HRID 1721522Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:21])[C@H:5]([CH2:9][C:10]1[C:15]([I:16])=[CH:14][C:13]([O:17]C)=[C:12]([O:19]C)[CH:11]=1)[NH:6][CH:7]=[O:8])[CH3:2].B(Br)(Br)Br>>[CH2:1]([O:3][C:4](=[O:21])[C@H:5]([CH2:9][C:10]1[C:15]([I:16])=[CH:14][C:13]([OH:17])=[C:12]([OH:19])[CH:11]=1)[NH:6][CH:7]=[O:8])[CH3:2]

Participants

Reactant 2

HCID 25134Boron tribromide

HCID 11122367N-formyl-3,4-dimethoxy-6-iodo-L-phenylalanine ethyl ester

Product 1

HCID 10937745N-formyl-3,4-dihydroxy-6-iodo-L-phenylalanine ethyl ester

Procedure

exposing the product of step (2) to BBr3 to form N-formyl-3,4-dihydroxy-6-iodo-L-phenylalanine ethyl ester,

Sources & evidence

ORD record: ord-eccbe821b325492ca227023299b5d35e
Source dataset: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05510522

Reaction notes

Loading…