反应详情

meso-Hydrobenzoin (mg 250, 1.17 mmol) was added to a solution of o-iodoxybenzoic acid I (820 mg, 2.93 mmol) in DMSO (15 ml). After 2 hours the solution was diluted with water, filtered and extracted with diethyl ether (3×15 ml). The combined organic layers were washed with water (2×5 ml), dried over sodium sulfate and evaporated to dryness under vacuum. The residue was triturated with n-hexane to give 228 mg (93%) of benzil, mp 91°-94° C. (lit. 94°-95° C.)

1. filtrationfiltered
2. extractionextracted with diethyl ether (3×15 ml)
3. washThe combined organic layers were washed with water (2×5 ml)
4. dry with materialdried over sodium sulfate
5. customevaporated to dryness under vacuum
6. customThe residue was triturated with n-hexane