HCID 22413361, compound → HCID 22413371, compound

HRID 1721598Notes

Reaction equation

HRID 1721598 reaction equation
[OH:1][C:2]1[CH:19]=[CH:18][C:5]2[CH:6]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[CH2:7][N:8]([CH3:11])[CH2:9][CH2:10][C:4]=2[C:3]=1[N+:20]([O-])=O>C(O)C.[Pd]>[NH2:20][C:3]1[C:4]2[CH2:10][CH2:9][N:8]([CH3:11])[CH2:7][CH:6]([C:12]3[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=3)[C:5]=2[CH:18]=[CH:19][C:2]=1[OH:1]

Participants

4

Reactant 1

HCID 22413361HCID 22413361, compound

Product 1

HCID 22413371HCID 22413371, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

0.16 g (0.00053 mol) 7-hydroxy-3-methyl-6-nitro-1 -phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine was dissolved in 15 ml ethanol. 0.05 g 10%Pd/C-catalyst were added and hydrogenation was carried out at a burette apparatus for 2h. The catalyst was filtered off and the solution was concentrated in vacuo. The compound was obtained as a light brown powder.

Workup

  1. filtrationThe catalyst was filtered off
  2. concentrationthe solution was concentrated in vacuo
  3. customThe compound was obtained as a light brown powder

Sources & evidence

ORD record
ord-2eb5318fc41646eebd4ee7275a132ff6
Source dataset
uspto-grants-1996_04
Patent number
US05512562

Reaction notes

Loading…