反应详情

Using a procedure similar to that described in example 21 except starting with 2-chloro-9-formyl-9,10-dihydro-9,10-methanoanthracene (described in example 1i) and 4-(4-fluorophenyl)-4hydroxypiperidine, the title compound hydrochloride salt was obtained in 27% yield as a white powder, mp 280°-281° C. elemental Analysis for C27H25ClFNO.HCl.0.5H2O: Calculated: C, 67.64; H, 5.68; N, 2.92 Found: C, 67.70; H, 5.40; N, 2.84.