HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyanobenzoic acid → 3-Cyanobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyanobenzoic acid | HCID 15875 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Cyanobenzoyl chloride | HCID 308483 | — |
Reaction Steps
A mixture of 50 g. of 3-cyanobenzoic acid and 100 ml. of thionyl chloride were stirred overnight in 500 ml. of methylene chloride. The solvent and excess thionyl chloride were removed in vacuo providing 55.3 g. of crude subtitle intermediate which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04853398 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-8a42c39f526347dca658a20abd808431 |
| Source note | uspto-grants-1989_08 |