1-(2-Hydroxyphenyl)-3-(1H-indol-4-yl)prop-2-en-1-one → 1-(2-Hydroxyphenyl)-3-(1H-indol-4-yl)propan-1-one

Participants

Reaction Steps

A mixture of 200 mg of the product of Step A in 10 ml of methanol was hydrogenated in the presence of palladized carbon until absorption ceased and was then filtered. Chromatography over silica and elution with a 6-3-1 cyclohexane-dichloromethane-triethylamine mixture yielded 143 mg of 1-[2-hydroxy-phenyl]-3-[1H-indol-4-yl]-1-propanone melting at 143° C.

Provenance & Evidence