HCID 178521466, compound → HCID 178521465, compound

Participants

Reaction Steps

A mixture of 3-[p-[4-(2-thienyl)-2-imidazolyl]phenoxyl]-1,2-propanediol acetonide (14.15 g, 0.04 m) in 3N HCl (80 ml) and acetone (80 ml) is refluxed for 0.5 hours. Acetone is removed under reduced pressure and the aqueous mixture is rendered alkaline with K2CO3. The solid is collected and dried in a vacuum oven at 60° C. to yield (III) (10.38 g, 82%, m.p. 197°-200° C.).

Provenance & Evidence