HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178488918, compound → HCID 178515896, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178488918 | HCID 178488918 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Hydrogen Bromide | HCID 260 | — |
| Product | HCID 178515896 | HCID 178515896 | 73.2% |
Reaction Steps
A suspension of 9 (2.5 g, 0.008 mol) in AcOH (10 ml) and 48% HBr (40 ml) was heated at reflux for 15 hours. The solution was concentrated to dryness and stirred overnight with saturated NaHCO3. The suspension was filtered, the solids chromatographed on silica gel and eluted with 5% CH3OH-CHCl3 to yield 1.4 g (65%) of 11. An analytical sample was prepared by crystallization from CH3CN, m.p. 210°-212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04853383 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-95fbac94c275486fb2a096d101dc4bb6 |
| Source note | uspto-grants-1989_08 |