Chlorosulfonic acid → 114322-12-2

HRID 1722192Notes

Reaction equation

HRID 1722192 reaction equation
[Cl:1][S:2]([OH:5])(=O)=[O:3].[CH3:6][O:7][C:8]1[CH:9]=[CH:10][C:11]2[S:15][N:14]=[N:13][C:12]=2[CH:16]=1>>[CH3:6][O:7][C:8]1[C:16]([S:2]([Cl:1])(=[O:5])=[O:3])=[C:12]2[N:13]=[N:14][S:15][C:11]2=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 24638Chlorosulfonic acidHCID 124949975-Methoxy-1,2,3-benzothiadiazole

Product 1

HCID 14180036114322-12-2

Procedure

To a stirred solution of 50 mL of chlorosulfonic acid at 0° C. was added 4.15 g of 5-methoxy-1,2,3-benzothiadiazole under an inert atmosphere. The resulting mixture was heated at reflux for 30 minutes. After cooling to room temperature, the reaction mixture was added to 600 mL ice-water mixture. The precipitate was collected, washed with water and ether, and air dried to give 5.6 g of the title compound as a white solid, m.p. 131°-134° C.

Workup

  1. temperatureThe resulting mixture was heated
  2. temperatureat reflux for 30 minutes
  3. customThe precipitate was collected
  4. washwashed with water and ether, and air
  5. customdried

Sources & evidence

ORD record
ord-14a0f2b0feea477080362c3e734dd25d
Source dataset
uspto-grants-1989_08
Patent number
US04854962

Reaction notes

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