Acetic Acid → HCID 13799209, compound

Participants

Reaction Steps

1.15 g of 5,6,7,8-tetrahydro-4-methoxymethyl-betacarboline-3-carboxylic acid ethyl ester is refluxed in 45 ml of ethanol with 5 ml of 2N aqueous potassium hydroxide solution for 2 hours. After cooling, it is acidified with glacial acetic acid. The precipitated product is suctioned off; the mother liquor is concentrated to approximately 30 ml. The precipitated product is again suctioned off. 1 g of 5,6,7,8-tetrahydro-4-methoxymethyl-beta-carboline-3carboxylic acid with a melting point greater than 260° C. is obtained.

Provenance & Evidence