Thiophenol → HCID 178449600, compound

HRID 1722262Notes

Reaction equation

HRID 1722262 reaction equation
[NH2:1][C@:2]([C:6]([NH:8][C@H:9]([C:17]([NH:19][C@H:20]([C:39]([OH:41])=[O:40])[CH2:21][C:22]1[N:26]=[CH:25][N:24](C2C=CC([N+]([O-])=O)=CC=2[N+]([O-])=O)[CH:23]=1)=[O:18])[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:7])([CH2:4][CH3:5])[CH3:3].C1(C[N-]C[C@@H](O)[CH2:52][CH2:53][OH:54])CCCCC1.C1(S)C=CC=CC=1>>[NH2:1][C@:2]([C:6]([NH:8][C@H:9]([C:17]([NH:19][C@H:20]([C:39]([OH:41])=[O:40])[CH2:21][C:22]1[N:26]=[CH:25][NH:24][CH:23]=1)=[O:18])[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:7])([CH2:4][CH3:5])[CH3:3].[CH:11]1([CH2:10][C@H:9]([NH-:8])[C@@H:17]([OH:18])[CH2:52][CH2:53][OH:54])[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]1

Participants

3

Reactant 2

HCID 7969ThiophenolHCID 131716020HCID 131716020, compound

Product 1

HCID 178449600HCID 178449600, compound

Procedure

310 mg of Iva-Phe-His(DNP)-cyclohexylmethyl-2(S),4-dihydroxybutylamide are reacted with thiophenol to give the title compound in analogy to reference example 1a.

Sources & evidence

ORD record
ord-b41e978136364991b20e3597496da62d
Source dataset
uspto-grants-1989_08
Patent number
US04855286

Reaction notes

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