HCID 67865980, compound → HCID 131716025, compound

Participants

Reaction Steps

790 mg of 4(S)-cyclohexylmethyl-5(R,S)-(1-methylimidazol-2-yl-methyl)-1,3-oxazolidin-2-one are dissolved in 33 ml of 2N LiOH in MeOH/H2O 1:1; and the solution is heated under reflux for 3 h, then diluted with 150 ml of water and extracted 3 times with 50 ml of CH2Cl2. Drying with Na2SO4 and concentration in vacuo results in the title compound as colorless oil which is used further without purification.

Provenance & Evidence