Carbon tetrabromide → HCID 14180975, compound

Participants

Reaction Steps

Triphenylphosphine (149 mg) in dry CH2Cl2 (0.5 ml) was added dropwise at -10° to -5° under nitrogen to a stirred solution of the compound of section (a) (155 mg) and CBr4 (139 mg) in dry CH2Cl2 (10 ml). After stirring at room temperature for 20 h (overnight) the solution was evaporated in the presence of silica gel and the resultant fine powder was chromatographed [elution with EA:hexane (1:1)] to give the title compound as a pale yellow viscous oil (117 mg). T.l.c. EA, Rf 0.51 (major).

Provenance & Evidence