Acetic Anhydride → HCID 54242499, compound

HRID 1722433Notes

Reaction equation

HRID 1722433 reaction equation
Br.[OH:2][C:3]1[CH:8]=[CH:7][C:6]([P:9]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][CH:4]=1.[C:23]([O-:26])(=O)[CH3:24].[Na+].[C:28](OC(=O)C)(=[O:30])[CH3:29]>O>[C:28]([O:2][C:3]1[CH:8]=[CH:7][C:6]([P:9]([C:16]2[CH:17]=[CH:18][C:19]([O:22][C:23](=[O:26])[CH3:24])=[CH:20][CH:21]=2)[C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:5][CH:4]=1)(=[O:30])[CH3:29]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 517045Sodium AcetateHCID 14548454HCID 14548454, compound

Product 1

HCID 54242499HCID 54242499, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 18.76 g (0.05 mol) of bis(4-hydroxyphenyl)phenylphosphine hydrobromide, 9.1 g (0.11 mol) of sodium acetate and 61 ml of acetic anhydride was heated at reflux for 4 hr and cooled. The mixture was poured onto a mixture of ice and water and the resultant solid was collected and recrystallized from methanol. The yield of bis(4-acetoxyphenyl)phenylphosphine was 4.9 g (25.9% of theory); mp=118°-20° C.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 4 hr
  3. temperaturecooled
  4. customthe resultant solid was collected
  5. customrecrystallized from methanol

Sources & evidence

ORD record
ord-878e02ed386f44f0be270807f78f6caf
Source dataset
uspto-grants-1989_08
Patent number
US04855396

Reaction notes

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