Carbon Dioxide → HCID 14279609, compound

HRID 1722474Notes

Reaction equation

HRID 1722474 reaction equation
[C:1]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:17]=1[NH:16][CH:15]=[C:14]2[CH2:18][CH:19](C(O)=O)[C:20]([OH:22])=[O:21])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)=O>>[C:1]([C:9]1[CH:10]=[CH:11][CH:12]=[C:13]2[C:17]=1[NH:16][CH:15]=[C:14]2[CH2:18][CH2:19][C:20]([OH:22])=[O:21])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 280Carbon DioxideHCID 14279607HCID 14279607, compound

Product 1

HCID 14279609HCID 14279609, compoundYield 100%

Procedure

A 2.4 g (0.07 mole) sample of 2-[(7-benzoyl-1H-indol-3-yl)methyl]propanedioic acid was heated at 190° C. under vacuum until carbon dioxide evolution ceased (1/2 hr). The syrup was cooled to give 2.1 g (100%) of a yellow solid, m.p. 166.5°-168-5° C.

Workup

  1. custom(1/2 hr)
  2. temperatureThe syrup was cooled

Sources & evidence

ORD record
ord-5e826932aba3442db9c7eb0dcf757092
Source dataset
uspto-grants-1989_08
Patent number
US04855448

Reaction notes

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