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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 172250Generated: October 30, 2026

1-(6-Chloro-2-methylpyridin-3-yl)ethanol → 5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(1-hydroxyethyl)-6-methylpyridin-2-yl]amino}thiophene-3-carboxamide

https://huagongshe.com/reaction/172250

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Chloro-2-methylpyridin-3-yl)ethanolHCID 59525596—
Reactant2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525619—
Product5-[2,6-Difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-{[5-(1-hydroxyethyl)-6-methylpyridin-2-yl]amino}thiophene-3-carboxamideHCID 59525657—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-8ea379e070e54a718b5f1b2ad864820c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)