HuagongsheHuagongshe Chemistry Print Report · For research reference only
(αR)-4-Methoxy-α-methylbenzeneethanamine → HCID 54051299, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (αR)-4-Methoxy-α-methylbenzeneethanamine | HCID 6951129 | — |
| Reactant | 5-(2,2-Dihydroxyacetyl)-8-(phenylmethoxy)-2(1H)-quinolinone | HCID 13744906 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 54051299 | HCID 54051299 | 75% |
Reaction Steps
One g of 8-benzyloxy-5-(dihydroxyacetyl)carbostiril 1/3 hydrate and 520 mg of (R)-N-(2-(p-methoxyphenyl)-1-methylethyl)amine are dissolved in 10 ml of dimethylsulfoxide, and the solution is stirred at room temperature for one hour. After the reaction is completed, the mixture is treated in the same manner as described in Example 10-(1). 1.06 g of 8-benzyloxy-5-{1-oxo-2-[N-((1R)-2-(p-methoxyphenyl)-1-methylethyl)imino]ethyl}carbostyril are obtained as pale yellow scales. Yield: 75%
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE033024 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-874dcd284ec341f4af5a933cddfdc478 |
| Source note | uspto-grants-1989_08 |