Hydrochloric Acid → HCID 20026909, compound

Participants

Reaction Steps

A mixture of 1.7 g of 2-allenyloxyphenylsulfonamide, 2.08 g of 4-methoxy-6-methyl-1,3,5-triazin-2-ylphenylcarbamate, 1.22 g of 1,8-diazabicyclo[5.4.0]undec-7-ene (1.5-5) and 150 ml of absolute dioxane is stirred for 4 hours at 20°-25° C. The reaction mixture is poured into water and, after adjusting the pH 6 by the dropwise addition of 10% hydrochloric acid, extracted with ethyl acetate. The organic phase is dried and concentrated by evaporation. The residue is crystallised from ethyl acetate to give 1.8 g of the title compound of m.p. 150°-151° C. (dec.

Provenance & Evidence