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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 17227Generated: October 26, 2026

1-Methyl-1H-indole-2-carbonyl chloride → N-[4-(4-amino-7-{[3-(4-methylpiperazin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide

https://huagongshe.com/reaction/17227

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-indole-2-carbonyl chlorideHCID 12303314—
ReactantHCID 18451407HCID 18451407—
ProductN-[4-(4-amino-7-{[3-(4-methylpiperazin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamideHCID 18451129—

Reaction Steps

The title compound was prepared using 1-methyl-1H-indole-2-carbonyl chloride, N-[4-amino-3-(4-amino-3-methoxyphenyl)thieno[3,2-c]pyridin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide, and the procedure described in General Procedure F. m/z (M+H)+ 598.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07737160B2
Source datasetuspto-grants-2010_06
ORD IDord-8a2542e7b0084b959625a8e40ae323ff
Source noteuspto-grants-2010_06