HuagongsheHuagongshe Chemistry Print Report · For research reference only
Borane → 1-(3,5-Difluoro-4-methoxyphenyl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Borane | HCID 6331 | — |
| Reactant | HCID 178493647 | HCID 178493647 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-(3,5-Difluoro-4-methoxyphenyl)methanamine | HCID 14626469 | 50% |
Reaction Steps
The reaction of 3,5-difluoro-4-methoxybenzaldehyde methoxime, (7 g, 35 mmole) and 0.98M borane in tetrahydrofuran (46 ml) substantially as described in 1B above produced 3 g, (50%) of the title compound as a clear oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04857540 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-b461391a257146d89abd1587774e3651 |
| Source note | uspto-grants-1989_08 |