HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → 5-[5-(2,6-Dichloro-4-cyanophenoxy)pentyl]-3-methylisoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Chloroxynil | HCID 74685 | — |
| Reactant | 5-(5-Bromopentyl)-3-methylisoxazole | HCID 13544046 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Methyl t-butylether hexane | HCID 21982663 | — |
| Product | 5-[5-(2,6-Dichloro-4-cyanophenoxy)pentyl]-3-methylisoxazole | HCID 10472340 | — |
Reaction Steps
5-[5-(2,6-Dichloro-4-cyanophenoxy)pentyl]-3-methylisoxazole [IX; Y=(CH2)5, Z=N, R=CH3, R1 =2-Cl, R2 =6-Cl] was prepared from 13.4 g 3,5-dichloro-4-hydroxybenzonitrile, 23.2 g 5-(5-bromopentyl)-3-methylisoxazole, 20.7 g potassium carbonate and 15 g sodium iodide in 250 ml dimethylformamide, similar to the procedure of Example 4, and was obtained in the form of colorless crystals (11.6 g), m.p. 59-60° C. (from tertiary-butyl methyl ether-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04857539 |
| Source dataset | uspto-grants-1989_08 |
| ORD ID | ord-7ad49b9c9e0846e3ad8142ec17615339 |
| Source note | uspto-grants-1989_08 |