HCID 10037362, 화합물 → 3alpha-Acetylthioacetyl-2-(o-methoxyphenylthio)methyl-thiazolidine

HRID 1722835노트

반응식

HRID 1722835 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[S:9][CH2:10][CH:11]1[NH:15][CH2:14][CH2:13][S:12]1.[C:16]([CH2:19][C:20](Cl)=[S:21])(=[O:18])[CH3:17]>N1C=CC=CC=1.OS(O)(=O)=O>[C:16]([CH2:19][C:20]([N:15]1[CH2:14][CH2:13][S:12][CH:11]1[CH2:10][S:9][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=1[O:2][CH3:1])=[S:21])(=[O:18])[CH3:17]

참가 물질

5

반응물 2

HCID 10037362HCID 10037362, 화합물HCID 23301560Acetylthioacetylchloride

생성물 1

HCID 200276313alpha-Acetylthioacetyl-2-(o-methoxyphenylthio)methyl-thiazolidine

시약·촉매·용매 2

HCID 1049Pyridine용매HCID 1118Sulfuric Acid용매

실험 절차

A solution of 2-(o-methoxyphenylthio)methyl-thiazolidine (5 g) in pyridine (25 ml) is reacted with acetylthioacetylchloride (2.93 g) for a night at room temperature, the reaction mixture is diluted with 2N H2SO4, extracted with ethylether to give after the usual work-up 3α-acetylthioacetyl-2-(o-methoxyphenylthio)methyl-thiazolidine, m.p. 62°-64° C.

후처리

  1. extractionextracted with ethylether

출처 및 근거

ORD 기록
ord-68b9a772d3dd44dfbe59c4b884ad4d52
출처 데이터셋
uspto-grants-1989_08
특허 번호
US04857643

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