HRID17229

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12303314

1-Methyl-1H-indole-2-carbonyl chloride

C10H8ClNO

结构：CCN(CC)CCC(=O)Nc1cnc(N)c2c(-c3ccc(N)c(OC)c3)csc12

HCID18451408

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)CCC(=O)Nc1cnc(N)c2c(-c3ccc(NC(=O)c4cc5ccccc5n4C)c(OC)c3)csc12

HCID18451165

未命名化合物

PROCEDURE

实验过程

The title compound was prepared using 1-methyl-1H-indole-2-carbonyl chloride, N-[4-Amino-3-(4-amino-3-methoxyphenyl)thieno[3,2-c]pyridin-7-yl]-3-diethylaminopropionamide, and the procedure described in General Procedure F. m/z (M+H)+ 571.3.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b9034ef6acf54c20aabf19eeb7ab85dd
来源数据集: uspto-grants-2010_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07737160B2
来源说明: uspto-grants-2010_06

反应 SMILES

[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]1[C:11](Cl)=[O:12].[NH2:14][C:15]1[C:20]2[C:21]([C:24]3[CH:29]=[CH:28][C:27]([NH2:30])=[C:26]([O:31][CH3:32])[CH:25]=3)=[CH:22][S:23][C:19]=2[C:18]([NH:33][C:34](=[O:42])[CH2:35][CH2:36][N:37]([CH2:40][CH3:41])[CH2:38][CH3:39])=[CH:17][N:16]=1>>[NH2:14][C:15]1[C:20]2[C:21]([C:24]3[CH:29]=[CH:28][C:27]([NH:30][C:11]([C:3]4[N:2]([CH3:1])[C:10]5[C:5]([CH:4]=4)=[CH:6][CH:7]=[CH:8][CH:9]=5)=[O:12])=[C:26]([O:31][CH3:32])[CH:25]=3)=[CH:22][S:23][C:19]=2[C:18]([NH:33][C:34](=[O:42])[CH2:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41])=[CH:17][N:16]=1